GW843682X

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Cat No.

CEI-1359

Product Overview

GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). GW843682X displays >100-fold selectivity over 30 other kinases tested including cdk1 and cdk2.GW843682X inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts.

CAS_No

660868-91-7

Molecular Weight

477.46

Purity

0.98

Storage

Store at -20°C

Synonyms

GW 843682X; GW843682; GW-843682X

Targets

PLK1/PLK3

Molecular Formula

C22H18F3N3O4S

Chemical Name

5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide

Solubility

Soluble in DMSO > 10 mM

Shipping Conditions

Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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