Hck from Human, Recombinant

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Cat No.

NATE-0335

Description

Hck is a member of the Src family of non-receptor associated protein tyrosine kinases (PTK). Hck has been shown to associate with and be activated by Bcr-Abl, which is a protein-tyrosine kinase that is expressed in chronic myelogenous leukemia.

Abbr

Hck, Recombinant (Human)

Alias

HCK; JTK9; p59Hck; p61Hck;

Source

E. coli BL21

Species

Human

Applications

Hck is a protein-tyrosine kinase that is expressed in hemopoietic cells. It is used in leukemia research

Package

vial of > 200 units

Form

Supplied as a solution in 50 mM Tris HCl, pH 7.4, 1 mM EDTA and 1 mM DTT

Activity

> 200 units

Unit Definition

One unit will phosphorylate 1.0 picomole of Tyr15 of the peptide substrate pcdc2 6-20 per minute at 30°C at pH 7.4.

Storage

−70°C

Pathway

Alpha-synuclein signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class I PI3K signaling events, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem

Function

ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein tyrosine kinase activity

Synonyms

Hck; HCK; tyrosine-protein kinase HCK; JTK9; p59Hck; p61Hck

"Hck" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0334	Hck from Human, Recombinant			Baculovirus infected insect cells	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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