homospermidine synthase

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Cat No.

EXWM-2780

Description

The reaction of this enzyme occurs in three steps, with some of the intermediates presumably remaining enzyme-bound: NAD+-dependent dehydrogenation of putrescine, transfer of the 4-aminobutylidene group from dehydroputrescine to a second molecule of putrescine and reduction of the imine intermediate to form homospermidine. Hence the overall reaction is transfer of a 4-aminobutyl group. Differs from EC 2.5.1.45, homospermidine synthase (spermidine-specific), which cannot use putrescine as donor of the aminobutyl group.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 2.5.1.44

CAS_No

76106-84-8

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Reaction

(1) 2 putrescine = sym-homospermidine + NH3 + H+; (2) putrescine + spermidine = sym-homospermidine + propane-1,3-diamine

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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