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Hydroxyacid Oxidase 1 from Human, Recombinant
Cat No.
NATE-3041
Description
Glycolate oxidase (HAO1) is a part of the superfamily of the alpha hydroxy acid oxidases (HAO) enzymes. HAO1 catalyses the FMN mediated oxidation of glycolate to glyoxylate and glyoxylate to oxalate by reducing oxygen to hydrogen peroxide. HAO1 is expressed mainly in the liver and pancreas and is most active on twocarbon substrates such as glycolate. HAO1 isthe main cause of hyperoxaluria, a disorder in which large deposits of calcium oxalate form kidney stones.
Source
Escherichia Coli.
Form
HAO1 protein solution (1mg/ml) contains 20% glycerol, 20mM Tris-Hcl (pH8.0) and 0.5M NaCl.
Enzyme Commission Number
EC 1.1.3.15
Activity
> 3000 pmol/min/ug
CAS No.
9028-71-1
Molecular Weight
45.0kDa
Purity
> 95 % (SDS-PAGE)
Storage
Store at -20°C.
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