interstitial collagenase

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Cat No.

EXWM-4353

Description

The enzyme takes its name from substrates of the interstitial collagen group - types I, II and III, all of which are cleaved in the helical domain. However, α-macroglobulins are cleaved much more rapidly. The enzyme is widely distributed in vertebrate animals. Type example of peptidase family M10

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.4.24.7

CAS_No

9001-12-1

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

vertebrate collagenase; matrix metalloproteinase 1

Reaction

Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775┼Ile in the α1(I) chain. Cleaves synthetic substrates and α-macroglobulins at bonds where P1' is a hydrophobic residue

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"Matrix Metalloproteinase" Total Products Page

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