IQ-1

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Cat No.

CEI-0711

Description

Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β-cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency.

Appearance

Off-white solid

Product Overview

A stem cell differentiating agent

CAS_No

331001-62-8

Molecular Weight

509.72

Purity

>98% by HPLC

Storage

-20 centigrade

Targets

PP2A

Molecular Formula

C₂₁H₂₂N₄O₂

Chemical Name

2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide

Solubility

DMSO (10 mM)

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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