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Cat No.

CEI-0595

Description

Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling IC50 = 27 nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which adds a palmitoyl group to Wnt proteins that is essential to their signaling ability and is required for Wnt secretion.

Appearance

White to off-white solid

Product Overview

An inhibitor of Wnt secretion and processing

CAS_No

686770-61-6

Molecular Weight

201.25

Purity

>98% by TLC

Storage

-20 centigrade

Targets

PORCN

Molecular Formula

C₂₂H₁₈N₄O₃S₃

Chemical Name

N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide

Solubility

DMSO

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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