IWP-3

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Cat No.

CEI-0615

Description

An inhibitor of Wnt production. Blocks Wnt pathway activity in vitro ( IC50 = 40 nM). IWP-3 inactivates Porcupine (Porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. Through blockade of Wnt signaling, IWP-3 has been used to promote cardiomyocyte generation from human embryonic stem cells (EC₅₀ = 1.2 µM).

Alias

Inhibitor of Wnt Production-3

Appearance

Off-white solid

Product Overview

An inhibitor of Wnt production

CAS_No

687561-60-0

Molecular Weight

211.22

Purity

>98%

Storage

-20 centigrade

Synonyms

Inhibitor of Wnt Production-3

Targets

phosphatsae

Molecular Formula

C22H17FN4O2S3

Chemical Name

2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2- d]pyrimidin-2-yl]thio]-N-(6-methyl-2-benzothiazolyl)-acetamide

Solubility

DMSO (10 mg/ml)

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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