JAK2 Inhibitor III, SD-1029

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Cat No.

CEI-1062

Description

A cell-permeable xanthenedione compound that acts as a JAK2-selective inhibitor. It exhibits much less effect on the cellular phosphorylation levels of Jak1 and Src and shows no significant inhibition towards a panel of 49 other protein kinases in cell-free kinase assays at a concentration of 10 µM. Effectively inhibits cell proliferation in JAK-activated BA/F3 cell lines as well as phosphorylation and nuclear translocation of cellular Stat3

Abbr

JAK2 Inhibitor III, SD-1029(JAK2)

Alias

JTK10, THCYT3

CAS_No

118372-34-2

Molecular Weight

639.3

Purity

>80% by HPLC (sum of isomers)

Storage

+2 centigrade to +8 centigrade

Synonyms

JTK10, THCYT3

Targets

JAK2

Molecular Formula

C25H30Cl2N2O3 • 2HBr

Chemical Name

9-(3,4-Dichlorophenyl)-2,7-bis(dimethylaminomethyl)-3,4,5,6,7,9-hexahydro-2H-xanthene-1,8-dione, 2HBr, NSC 371488

Solubility

DMSO

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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