JNJ-38877605

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Cat No.

CEI-0039

Description

JNJ-38877605 is a small-molecule, ATP-competitive inhibitor of the catalytic activity of c-Met.

CAS_No

943540-75-8

Molecular Weight

377.35

Purity

>99%

Storage

2 years at -20 centigrade

Targets

c-Met

Molecular Formula

C19H13F2N7

Chemical Name

6-(difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline

Solubility

DSMO 15 mg/mL Water

In vitro

JNJ-38877605 is a small-molecule, ATP-competitive inhibitor of the catalytic activity of c-Met. JNJ-38877605 showed around 600-fold selectivity for c-Met compared with a panel of 250 diverse tyrosine and serine-threonine kinases and was found to potently inhibit HGF-stimulated and constitutively activated c-Met phosphorylation in vitro.

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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