Lactacystin (Synthetic)

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Cat No.

CEI-0393

Description

Cell-permeable. A potent and selective inhibitor of the 20 S proteasome. Binds irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activities. Induces neurite outgrowth in Neuro 2A neuroblastoma cells and has been reported to induce apoptosis in human monoblast U937 cells. Also inhibits NF-kB activation (IC50 = 10 µM).

Appearance

White solid

Product Overview

A proteasome inhibitor

CAS_No

133343-34-7

Molecular Weight

360.43

Purity

>95% by HPLC

Storage

+4 centigrade

Targets

20 S proteasome

Molecular Formula

C₁₅H₂₄N₂O₇S

Solubility

DMSO (10 mg/ml)

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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