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Lactosyl Ceramide, Bovine


Cat No.
COEC-107
Description
Lactosyl Ceramide neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of ERK 1 (p44 MAP kinase). Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells.
Applications
An inducer of Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, c-fos expression
Form
Solid
CAS No.
4682-48-8
Molecular Weight
960.4
Purity
≥98%
Synonyms
Ceramide β-lactoside
Molecular Formula
C53H101NO13
Solubility
Soluble in ethanol, methanol, chloroform, and chloroform/methanol (91) (10 mg/ml).
Boiling Point
300° C
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