L-cysteine desulfidase

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Cat No.

EXWM-5330

Description

The enzyme from the archaeon Methanocaldococcus jannaschii contains a [4Fe-4S] cluster and is specific for L-cysteine (cf. EC 4.4.1.1, cystathionine γ-lyase). It cleaves a carbon-sulfur bond releasing sulfide and the unstable enamine product 2-aminoprop-2-enoate that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia. The same reaction can also be catalysed by some pyridoxal-phosphate proteins (cf. EC 4.4.1.1, cystathionine γ-lyase).

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 4.4.1.28

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

L-cysteine desulfhydrase

Reaction

L-cysteine + H2O = sulfide + NH3 + pyruvate (overall reaction); (1a) L-cysteine = 2-aminoprop-2-enoate + sulfide; (1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous); (1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous)

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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