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Letrozole

Cat No.
CEI-0351
Description
Letrozole
Alias
CGS 20267
CAS No.
112809-51-5
Molecular Weight
285.3
Purity
>99%
Storage
2 years at -20centigrade Powder
Synonyms
CGS 20267
Targets
estrogen receptors
Molecular Formula
C17H11N5
Solubility
DMSO 57 mg/mL, Water
In vitro
Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM. Letrozole potently inhibits aromatase derived from a variety of different sources including human placental microsomes, particulate fractions of human breast cancer, rat ovarian microsomes, MCF-7 cells transfected with aromatase (MCF-7Ca), JEG-3 human choriocarcinoma cells, CHO cells, hamster ovarian tissue, and particulate fractions of human breast cancer with IC50 of 11, 2, 7, 0.07, 0.07, 1.4, 20 and 0.8 nM.

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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