LFM-A13

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Cat No.

CEI-0966

Description

Potent and selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits recombinant BTK with an IC50 = 2.5 uM and has no activity at other protein kinases (including JAK1, JAK3, HCK, EGFR kinase and insulin receptor kinase) at concentrations up to 300 uM.

Abbr

LFM-A13(BTK)

Alias

2-Cyano-N-(2, 5-dibromophenyl)-3-hydroxy-2-butenamide

Appearance

Yellow powder

Product Overview

BTK Inhibitor

CAS_No

62004-35-7

Molecular Weight

360.0

Purity

98% (TLC: 2:8 CH3OH:CH2Cl2; Rf=0.53); NMR (Conforms)

Synonyms

2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide

Targets

BTK

Molecular Formula

C11H8Br2N2O2

Melting Point

145-146ºC

Solubility

DMSO (10 mg/ml) and ethanol (15 mg/ml)

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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