L-Methionine γ-Lyase, Recombinant

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Cat No.

NATE-0414

Description

L-Methionine γ-Lyase or methioninase has been shown to have anti-tumor effects by depleting methionine from methionine-dependent tumors making them more sensitive to traditional chemotherapies.

Abbr

L-Methionine γ-Lyase, Recombinant

Source

E. coli

Applications

L-Methionine γ-lyase has been used in a study to assess catabolism of volatile sulfur compound precursors by Brevibacterium linens and Geotrichum candidum. It has also been used in a study to investigate the enzymatic pr ocessing of fluorinated methionine analogs.

Product Overview

L-Methionine γ-lyase is a pyridoxal phosphate-containing enzyme that converts L-methionine to α-ketobutyrate, ammonia and methyl mercaptan.

Form

Supplied as a lyophilized powder containing pyridoxal-5′-phosphate and potassium phosphate

Enzyme Commission Number

EC 4.4.1.11

Activity

> 0.2 unit/mg solid

CAS_No

42616-25-1

Unit Definition

One unit iwill convert 1 micromole of L-methionine to 2-ketobutyrate per minute at pH 7.0 at 37°C.

Storage

−20°C

Warnings

Expressed in E. coli from a proprietary gene

Synonyms

L-methioninase; methionine lyase; methioninase; methionine dethiomethylase; L-methionine γ-lyase; L-methionine methanethiol-lyase (deaminating); EC 4.4.1.11; methionine γ-lyase

"L-Methionine γ-Lyase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1655	L-Methionine γ-Lyase from Pseudomonas putida, Recombinant	EC 4.4.1.11		E. coli	Inquiry
EXWM-5314	methionine γ-lyase	EC 4.4.1.11	42616-25-1		Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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