LYS6K2

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Cat No.

CEI-0967

Description

A selective inhibitor of the p70 ribosomal S6 kinase (S6K). Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 uM with no activity at GSK3beta and Erk1/2 at 10 uM. Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K. Cell permeable.

Abbr

LYS6K2(RPS6KB1)

Alias

4-(4-(4-(4-fluoro-3-(trifluoromethyl) phenyl)-1-methyl-1H-imidazol-2-yl) piperidin-1-yl)-1H-pyrazolo [3, 4-d] pyrimidine

Appearance

Yellow solid

Product Overview

S6K Inhibitor

CAS_No

1082949-67-4

Molecular Weight

445.4

Purity

>97% (HPLC); NMR (Conforms)

Synonyms

4-(4-(4-(4-fluoro-3-(trifluoromethyl) phenyl)-1-methyl-1H-imidazol-2-yl) piperidin-1-yl)-1H-pyrazolo [3,4-d] pyrimidine

Targets

S6K

Molecular Formula

C21H19F4N7

Melting Point

276-280ºC

Solubility

May be dissolved in DMSO (1 mg/ml); DMF (3 mg/ml, warm)

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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