memapsin 2

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Cat No.

EXWM-4283

Description

Suggested to be the major "β-secretase" responsible for the cleavage of the β-amyloid precursor protein to form the amyloidogenic β-peptide that is implicated in the pathology of Alzheimers disease. In peptidase family A1 but is atypical in containing a C-terminal membrane-spanning domain.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 3.4.23.46

CAS_No

158736-49-3

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

β-secretase; β-site Alzheimers amyloid precursor protein cleaving enzyme 1 (BACE1)

Reaction

Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu┼Asp-Ala-Glu-Phe in the Swedish variant of Alzheimers amyloid precursor protein

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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