Merck-22-6

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Cat No.

CEI-1124

Description

Merck-22-6 is a potent, allosteric dual Akt1, Akt2 inhibitor with IC50=138nM and 212nM respectively. Selective over Akt3, IC50=7200nM.

Abbr

Merck-22-6(AKT1, AKT2, AKT3)

Alias

AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA

Product Overview

Akt1, Akt2 inhibitors

CAS_No

12847-42-4

Molecular Weight

653.82

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

4 centigrade

Synonyms

AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA

Targets

Akt1, Akt2, Akt3

IC50

138nM, 212nM, 7200nM

Molecular Formula

C40H43N7O2

Chemical Name

N-(2-(diethylamino)ethyl)-3-(4-((4-(2-oxo-2,3-dihydro-benzo[d]imidazol-1-yl)piperidin-1-yl)methyl)phenyl)-2-phenylquinoxaline-6-carboxamide

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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