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MIF antagonist, p425
Cat No.
CEI-0567
Description
A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. Acts as an allosteric MIF (macrophage migration inhibitory factor) inhibitor. It occupies an interface of MIF trimers, leading to the loss of its tautomerase, receptor binding, and pro-inflammatory activities. An excellent tool to design MIF-directed therapeutics for inflammatory diseases.
Alias
Chicago Sky blue 6B
Appearance
Off-white solid
Product Overview
An allosteric MIF (macrophage migration inhibitory factor) inhibitor
CAS No.
259444
Molecular Weight
281.35
Purity
>95%
Storage
-20 centigrade
Synonyms
Chicago Sky blue 6B
Targets
Microtubule
Molecular Formula
C 34 H 24 N 6 Na 4 O 16 S 4
Chemical Name
6,6-[(3,3-Dimethoxy[1,1-biphenyl]-4,4-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonic acid] tetrasodium salt
Solubility
DMSO or EtOH
Shipping Conditions
RT
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