ML130

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Cat No.

CEI-0594

Description

Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC₅₀ = 0.56±0.04 µM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-⍺-induced NF-kB activation.

Alias

Nodinitib-1

Appearance

White solid

Product Overview

A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor

CAS_No

799264-47-4

Molecular Weight

280.32

Purity

>95% by HPLC

Storage

-20 centigrade

Synonyms

Nodinitib-1

Targets

NOD1

Molecular Formula

C₁₄H₁₃N₃O₂S

Chemical Name

1-Tosyl-1H-benzo[d]imidazol-2-amine

Solubility

DMSO or EtOH

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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