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ML130
Cat No.
CEI-0594
Description
Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC₅₀ = 0.56±0.04 µM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-⍺-induced NF-kB activation.
Alias
Nodinitib-1
Appearance
White solid
Product Overview
A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor
CAS No.
799264-47-4
Molecular Weight
280.32
Purity
>95% by HPLC
Storage
-20 centigrade
Synonyms
Nodinitib-1
Targets
NOD1
Molecular Formula
C₁₄H₁₃N₃O₂S
Chemical Name
1-Tosyl-1H-benzo[d]imidazol-2-amine
Solubility
DMSO or EtOH
Shipping Conditions
Gel pack
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