Myeloperoxidase Inhibitor

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Cat No.

CEI-0580

Description

A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC₂sub>50 = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H 2 O 2 -induced apoptosis in HL-60, human leukemia cells.

Alias

4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH

Appearance

Yellow to beige solid

Product Overview

A potent myeloperoxidase (MPO) inhibitor

CAS_No

5351-17-7

Molecular Weight

223.35

Purity

>97% by HPLC

Storage

-20 centigrade

Synonyms

4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH

Targets

MPO

Molecular Formula

C 7 H 9 N 3 O

Solubility

DMSO or EtOH

Shipping Conditions

Gel pack

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Project Description:

For research and industrial use only, not for personal medicinal use.

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