Nα-Boc-L-valyl-L-citrulline

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Cat No.

CEGZ-50012

Description

Nα-Boc-L-valyl-L-citrulline is a protected dipeptide building block composed of valine linked to citrulline, with the N-terminus masked by a Boc group and the C-terminal carboxyl group free for coupling.

Applications

Used as a building block in the synthesis of protease-cleavable linkers for antibody-drug conjugates and other targeted drug delivery research.

Product Overview

The Val-Cit motif is one of the most widely used protease-cleavable dipeptide sequences in the design of antibody-drug conjugate linkers, where it is recognized and cleaved by lysosomal proteases such as cathepsin B to release the payload.

CAS_No

870487-08-4

Molecular Weight

374.43

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Boc-valine-citrulline; N-tert-butoxycarbonyl-L-valyl-L-citrulline

Molecular Formula

C16H30N4O6

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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