Nα-Boc-Nω-Pbf-L-arginine

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Cat No.

CEGZ-6972

Description

Nα-Boc-Nω-Pbf-L-arginine is a protected arginine derivative in which the α-amino group carries a Boc group and the guanidino side chain is masked by the Pbf sulfonyl group. Both protections are removed under acidic conditions.

Applications

Used as a building block in peptide synthesis for the preparation of arginine-containing peptides and as an intermediate for arginine derivatives.

Product Overview

The Pbf group is the standard protection for the arginine side chain in modern peptide synthesis, preventing side reactions at the guanidino function during coupling. This derivative is used in Boc-strategy synthesis and in fragment condensation approaches.

CAS_No

200124-22-7

Molecular Weight

526.6

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Boc-Arg(Pbf); Nα-tert-butoxycarbonyl-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine

Molecular Formula

C24H38N4O7S

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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