Nα-Boc-N-methyl-L-alanine

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Cat No.

CEGZ-6993

Description

Nα-Boc-N-methyl-L-alanine is the N-methylated, Boc-protected form of the proteinogenic amino acid L-alanine. The N-methyl group eliminates the hydrogen-bond donor capacity of the α-amino function and restricts local backbone conformation.

Applications

Used as a building block in peptide synthesis and medicinal chemistry for the preparation of N-methylated peptide analogues.

Product Overview

N-Methyl amino acids are important tools in peptide medicinal chemistry because backbone N-methylation enhances proteolytic stability, membrane permeability, and conformational rigidity, and N-methylated residues occur in numerous peptide natural products and drug candidates.

CAS_No

16948-16-6

Molecular Weight

203.24

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Boc-N-methylalanine; N-tert-butoxycarbonyl-N-methyl-L-alanine

Molecular Formula

C9H17NO4

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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