Nα-Fmoc-1-aminocyclopentanecarboxylic Acid

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Cat No.

CEGZ-6945

Description

Nα-Fmoc-1-aminocyclopentanecarboxylic acid is the Fmoc-protected form of a cyclic α,α-disubstituted amino acid in which the α-carbon forms part of a cyclopentane ring. It is used as a building block in Fmoc solid-phase peptide synthesis.

Applications

Used in solid-phase peptide synthesis for the preparation of conformationally constrained peptides, foldamers, and protease-resistant peptide analogues.

Product Overview

α,α-Disubstituted amino acids of this type strongly restrict backbone conformational freedom and favor helical and turn structures, while also conferring high resistance to proteolytic degradation, properties exploited in the design of peptidomimetics and foldamers.

CAS_No

126705-22-4

Molecular Weight

323.3

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-ACPC-OH; N-(9-fluorenylmethoxycarbonyl)-1-aminocyclopentane-1-carboxylic acid

Molecular Formula

C19H17NO4

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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