Nα-Fmoc-2-methyl-L-proline

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Cat No.

CEGZ-50036

Description

Nα-Fmoc-2-methyl-L-proline is the Fmoc-protected form of α-methyl-L-proline, an α-methylated proline analogue in which the α-hydrogen is replaced by a methyl group, creating a quaternary α-carbon within the pyrrolidine ring.

Applications

Used as a building block in solid-phase peptide synthesis and medicinal chemistry for the preparation of conformationally constrained, protease-resistant peptide analogues.

Product Overview

α-Methylproline is a strongly conformationally constrained amino acid whose incorporation into peptides stabilizes defined turn and helical structures and confers high resistance to proteolytic degradation, properties exploited in peptidomimetic design.

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-α-methyl-L-proline; N-(9-fluorenylmethoxycarbonyl)-2-methyl-L-proline

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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