Nα-Fmoc-D-glutamic Acid α-tert-Butyl Ester

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Cat No.

CEGZ-6912

Description

Nα-Fmoc-D-glutamic acid α-tert-butyl ester is a protected D-glutamic acid derivative in which the α-carboxyl group is masked as a tert-butyl ester while the γ-carboxyl group remains free. This protection pattern allows chain extension through the side-chain carboxyl group or use of the compound in fragment condensation approaches.

Applications

Used as an intermediate in peptide synthesis for side-chain coupled glutamic acid derivatives, γ-linked peptides, and D-amino acid-containing peptide analogues in pharmaceutical research.

Product Overview

This derivative is complementary to the more common γ-protected glutamic acid building blocks. The free γ-carboxyl group can be selectively coupled or modified while the α-carboxyl and α-amino functions remain protected, which is useful in the synthesis of γ-linked peptides and glutamic acid-containing conjugates.

CAS_No

109745-15-5

Molecular Weight

425.5

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-D-glutamic acid 1-tert-butyl ester; N-(9-fluorenylmethoxycarbonyl)-D-glutamic acid α-tert-butyl ester

Molecular Formula

C24H27NO6

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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