Nα-Fmoc-Nβ-Alloc-L-2,3-diaminopropionic Acid

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Cat No.

CEGZ-6894

Description

Nα-Fmoc-Nβ-Alloc-L-2,3-diaminopropionic acid is an orthogonally protected diaminopropionic acid derivative for Fmoc solid-phase peptide synthesis. The allyloxycarbonyl (Alloc) group protects the β-amino side chain and is removed by palladium-catalyzed deallylation under nearly neutral conditions.

Applications

Used in solid-phase peptide synthesis for the introduction of diaminopropionic acid residues and for site-selective peptide modification, including the preparation of cyclic peptides and peptide conjugates.

Product Overview

The Alloc protecting group is orthogonal to both Fmoc and Boc chemistries, enabling selective side-chain deprotection for on-resin modification, cyclization, or conjugation at the diaminopropionic acid residue.

CAS_No

188970-92-5

Molecular Weight

410.4

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-Dap(Alloc); Nα-(9-fluorenylmethoxycarbonyl)-Nβ-(allyloxycarbonyl)-L-2,3-diaminopropionic acid

Molecular Formula

C22H22N2O6

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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