Nα-Fmoc-Nγ-Alloc-L-2,4-diaminobutyric Acid

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Cat No.

CEGZ-6899

Description

Nα-Fmoc-Nγ-Alloc-L-2,4-diaminobutyric acid is an orthogonally protected diaminobutyric acid derivative for Fmoc solid-phase peptide synthesis. The allyloxycarbonyl (Alloc) group on the γ-amino side chain is stable to both basic Fmoc deprotection and acidic Boc cleavage conditions, and is selectively removed by palladium-catalyzed deallylation.

Applications

Used in solid-phase peptide synthesis for the introduction of 2,4-diaminobutyric acid residues and for site-selective peptide modification in the preparation of cyclic peptides, branched peptides, and peptide conjugates.

Product Overview

This orthogonality allows selective exposure of the side-chain amino group on the solid support for branching, cyclization, labeling, or conjugation while the rest of the peptide remains fully protected.

CAS_No

204316-32-5

Molecular Weight

424.4

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-Dab(Alloc); Nα-(9-fluorenylmethoxycarbonyl)-Nγ-(allyloxycarbonyl)-L-2,4-diaminobutyric acid

Molecular Formula

C23H24N2O6

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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