Nα-Fmoc-Nα-methyl-Nγ-trityl-L-asparagine

inquiry

Cat No.

CEGZ-50043

Description

Nα-Fmoc-Nα-methyl-Nγ-trityl-L-asparagine is an N-methylated, side-chain protected asparagine derivative for Fmoc solid-phase peptide synthesis. The α-amino group bears a methyl group together with the Fmoc protection, and the side-chain carboxamide is masked by a trityl group.

Applications

Used in solid-phase peptide synthesis for the preparation of N-methylated peptide analogues with improved pharmacological properties.

Product Overview

Backbone N-methylation removes an amide hydrogen-bond donor, restricts local conformation, and improves the proteolytic stability and membrane permeability of peptides, while trityl protection prevents side reactions at the carboxamide during chain assembly.

CAS_No

941296-80-6

Molecular Weight

610.7

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-N-methyl-Asn(Trt); Nα-(9-fluorenylmethoxycarbonyl)-Nα-methyl-Nγ-trityl-L-asparagine

Molecular Formula

C39H34N2O5

Notes

For research and development use only.

First Name:

Last Name:

Email *

Phone Number:

Company/Institution:

Country or Region:

Quantity:

Services & Products of Interested *

Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

Products

Online Inquiry