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Enzymes for Research, Diagnostic and Industrial Use

Nα-Fmoc-Nγ,Nγ-dimethyl-L-asparagine

Cat No.
CEGZ-50038
Description
Nα-Fmoc-Nγ,Nγ-dimethyl-L-asparagine is an Fmoc-protected asparagine derivative in which the side-chain carboxamide nitrogen bears two methyl groups, converting the primary amide into a tertiary dimethylamide. It is used as a building block in Fmoc solid-phase peptide synthesis.
Applications
Used in solid-phase peptide synthesis for the preparation of side-chain modified asparagine-containing peptide analogues in pharmaceutical research.
Product Overview
N,N-Dimethylation of the asparagine side chain removes the amide hydrogen-bond donors and increases lipophilicity, a modification used to modulate peptide conformation, solubility, and proteolytic stability in structure-activity studies.
CAS_No
138585-02-1
Molecular Weight
382.4
Storage
Store in a tightly closed container in a cool, dry place.
Synonyms
Fmoc-N,N-dimethyl-L-asparagine; Nα-(9-fluorenylmethoxycarbonyl)-Nγ,Nγ-dimethyl-L-asparagine
Molecular Formula
C21H22N2O5
Notes
For research and development use only.

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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