Nα-Fmoc-Nγ-trityl-L-glutaminyl-glycine

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Cat No.

CEGZ-50041

Description

Nα-Fmoc-Nγ-trityl-L-glutaminyl-glycine is a protected dipeptide building block comprising glutamine, protected at the side-chain carboxamide with a trityl group, coupled to glycine, with the N-terminus masked by the Fmoc group. It is designed for direct incorporation of a Gln-Gly segment in Fmoc solid-phase peptide synthesis.

Applications

Applied in solid-phase peptide synthesis for the efficient introduction of glutamine-glycine segments into bioactive peptides and peptide intermediates.

Product Overview

Trityl protection of the glutamine side chain suppresses dehydration and other side reactions of the carboxamide group during coupling, while the use of a preformed dipeptide improves assembly efficiency at aggregation-prone sequences.

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-Gln(Trt)-Gly; Nα-(9-fluorenylmethoxycarbonyl)-Nγ-trityl-L-glutaminyl-glycine

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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