Nα-Fmoc-O-tert-butyl-L-hydroxyproline

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Cat No.

CEGZ-6900

Description

Nα-Fmoc-O-tert-butyl-L-hydroxyproline is a side-chain protected derivative of L-4-hydroxyproline for Fmoc solid-phase peptide synthesis. The tert-butyl ether protects the hydroxyl group of the pyrrolidine ring and is cleaved during final acidolytic deprotection.

Applications

Applied in solid-phase peptide synthesis for the preparation of collagen model peptides, proline-rich peptides, and other hydroxyproline-containing sequences for biochemical and pharmaceutical research.

Product Overview

Hydroxyproline is a characteristic residue of collagen and collagen-like peptides, and its incorporation into synthetic peptides is essential for studying collagen structure, stability, and recognition, as well as for the design of proline-rich bioactive peptides.

CAS_No

122996-47-8

Molecular Weight

409.5

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-hydroxyproline(tert-butyl); N-(9-fluorenylmethoxycarbonyl)-O-tert-butyl-L-4-hydroxyproline

Molecular Formula

C24H27NO5

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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