Nα-Fmoc-O-tert-butyl-L-seryl-L-threonine Pseudoproline Dipeptide

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Cat No.

CEGZ-6917

Description

Nα-Fmoc-O-tert-butyl-L-seryl-L-threonine pseudoproline dipeptide is a dipeptide building block in which the threonine residue is cyclized into a 2,2-dimethyloxazolidine (pseudoproline) ring. The pseudoproline is stable to standard coupling conditions and is converted back to threonine during final acidolytic deprotection.

Applications

Used in solid-phase peptide synthesis of aggregation-prone, hydrophobic, or long peptide sequences to improve solvation of the growing chain and to increase overall synthesis efficiency.

Product Overview

Pseudoproline dipeptides are established tools for disrupting interchain aggregation and β-sheet formation during solid-phase peptide synthesis, thereby improving coupling yields and crude purity in long or difficult peptide sequences.

CAS_No

1266350-99-5

Molecular Weight

524.6

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH; Fmoc-protected serine-threonine dimethyl pseudoproline dipeptide

Molecular Formula

C29H36N2O7

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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