Nα-Fmoc-S-trityl-D-cysteine

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Cat No.

CEGZ-6889

Description

Nα-Fmoc-S-trityl-D-cysteine is a protected D-cysteine derivative for Fmoc solid-phase peptide synthesis. The trityl group shields the thiol side chain against oxidation and alkylation during chain assembly and is removed by acidolysis, typically with trifluoroacetic acid-based cocktails.

Applications

Applied in solid-phase peptide synthesis for the preparation of disulfide-bridged peptides, cyclic peptides, and peptide analogues containing D-cysteine residues.

Product Overview

This building block enables the site-specific introduction of D-cysteine residues into synthetic peptides. D-Cysteine incorporation is valuable in the design of disulfide-constrained peptides with increased resistance to enzymatic degradation.

CAS_No

167015-11-4

Molecular Weight

585.7

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-D-cysteine(trityl); N-(9-fluorenylmethoxycarbonyl)-S-trityl-D-cysteine

Molecular Formula

C37H31NO4S

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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