Nα-Fmoc-trans-3-hydroxy-L-proline

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Cat No.

CEGZ-50022

Description

Nα-Fmoc-trans-3-hydroxy-L-proline is the Fmoc-protected form of trans-3-hydroxy-L-proline, a less common hydroxyproline isomer bearing the hydroxyl group at the 3-position of the pyrrolidine ring. It is used as a building block in Fmoc solid-phase peptide synthesis.

Applications

Used in solid-phase peptide synthesis for the preparation of conformationally constrained peptides and hydroxyproline-containing peptide analogues in biochemical research.

Product Overview

Hydroxyproline isomers introduce defined conformational constraints and hydrogen-bonding functionality into peptide backbones, and the 3-hydroxy isomer offers a distinct ring pucker and substituent presentation compared with the more common 4-hydroxyproline.

CAS_No

296774-32-8

Molecular Weight

353.4

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Fmoc-(2S,3S)-3-hydroxyproline; (2S,3S)-1-(9-fluorenylmethoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid

Molecular Formula

C20H19NO5

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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