N,N-Dimethyl-L-valine

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Cat No.

CEGZ-6902

Description

N,N-Dimethyl-L-valine is an N-terminally dimethylated derivative of the proteinogenic amino acid L-valine. The two N-methyl groups eliminate hydrogen-bond donor capacity at the amino terminus and increase the lipophilicity of the residue.

Applications

Used as a building block in peptide synthesis and medicinal chemistry for the preparation of N-methylated peptide analogues with improved stability and permeability, and in natural product synthesis research.

Product Overview

N-Methylated amino acids are important tools in peptide medicinal chemistry because backbone N-methylation enhances proteolytic stability, membrane permeability, and conformational rigidity of peptides. N,N-Dimethylated residues are also found at the N-termini of several peptide natural products.

CAS_No

2812-32-0

Molecular Weight

145.20

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

N,N-dimethylvaline; 2-(dimethylamino)-3-methylbutanoic acid

Molecular Formula

C7H15NO2

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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