Nα,Nin-di-Boc-L-tryptophan

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Cat No.

CEGZ-6923

Description

Nα,Nin-di-Boc-L-tryptophan is a fully Boc-protected tryptophan derivative for peptide synthesis, carrying tert-butoxycarbonyl groups on both the α-amino function and the indole nitrogen. Indole protection suppresses oxidation and alkylation side reactions of the tryptophan side chain during synthesis.

Applications

Used as a building block in solid-phase and solution-phase peptide synthesis for the preparation of tryptophan-containing peptides with reduced side-reaction risk.

Product Overview

The Nin-Boc group is removed during acidolytic deprotection, and its presence is particularly beneficial in sequences prone to tryptophan modification. The derivative is compatible with both Boc and Fmoc synthesis strategies.

CAS_No

144599-95-1

Molecular Weight

404.5

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Boc-Trp(Boc); Nα-tert-butoxycarbonyl-Nin-tert-butoxycarbonyl-L-tryptophan

Molecular Formula

C21H28N2O6

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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