Nα-Z-N,O-dimethyl-L-tyrosine

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Cat No.

CEGZ-6980

Description

Nα-Z-N,O-dimethyl-L-tyrosine is a doubly methylated, Z-protected tyrosine derivative in which the α-amino group bears a methyl group together with the benzyloxycarbonyl protection, and the phenolic hydroxyl group is present as a methyl ether.

Applications

Used as a building block in peptide synthesis and medicinal chemistry for the preparation of N-methylated peptide analogues and tyrosine derivatives.

Product Overview

N-Methyl amino acid building blocks are important tools in peptide medicinal chemistry because backbone N-methylation improves proteolytic stability, membrane permeability, and conformational definition of peptides. O-Methylation additionally masks the polar phenolic group.

CAS_No

118171-80-5

Molecular Weight

343.4

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Cbz-N-methyl-O-methyl-L-tyrosine; N-benzyloxycarbonyl-N-methyl-O-methyl-L-tyrosine

Molecular Formula

C19H21NO5

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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