Nα-Z-trans-3-hydroxy-L-proline

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Cat No.

CEGZ-50023

Description

Nα-Z-trans-3-hydroxy-L-proline is the benzyloxycarbonyl-protected form of trans-3-hydroxy-L-proline, a hydroxyproline isomer bearing the hydroxyl group at the 3-position of the pyrrolidine ring. The Z group is removed by hydrogenolysis or strong acid.

Applications

Used as a building block in peptide synthesis and as an intermediate in the preparation of hydroxyproline-containing peptides and pharmaceutical compounds.

Product Overview

Z-protected hydroxyproline building blocks are used in solution-phase peptide synthesis and in the preparation of conformationally constrained peptide intermediates, where the 3-hydroxy substituent offers distinct conformational properties.

CAS_No

62182-54-1

Molecular Weight

265.26

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

Cbz-trans-3-hydroxy-L-proline; (2S,3S)-1-benzyloxycarbonyl-3-hydroxypyrrolidine-2-carboxylic acid

Molecular Formula

C13H15NO5

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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