N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase

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Cat No.

EXWM-2455

Description

Involved in the biosynthesis of chondroitin and dermatan sulfate. The human chondroitin synthetase is a bifunctional glycosyltransferase, which has the 3-β-glucuronosyltransferase and 4-β-N-acetylgalactosaminyltransferase (EC 2.4.1.175) activities required for the synthesis of the chondroitin sulfate disaccharide repeats. Similar chondroitin synthase 'co-polymerases' can be found in Pasteurella multocida and Escherichia coli. There is also another human protein with apparently only the 3-β-glucuronosyltransferase activity.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 2.4.1.226

CAS_No

269077-98-7

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

chondroitin glucuronyltransferase II; α-D-glucuronate:N-acetyl-β-D-galactosaminyl-(1→4)-β-D-glucuronosyl-proteoglycan 3-β-glucuronosyltransferase

Reaction

UDP-α-D-glucuronate + N-acetyl-β-D-galactosaminyl-(1→4)-β-D-glucuronosyl-proteoglycan = UDP + β-D-glucuronosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-β-D-glucuronosyl-proteoglycan

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"Chondroitin synthase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1486	Chondroitin synthase from Pasteurella multocida, Recombinant	EC 2.4.1.226	269077-98-7	E. coli	Inquiry

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