Native Bacillus cereus Sphingomyelinase

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Cat No.

NATE-0672

Description

Sphingomyelin phosphodiesterase is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide. The activation of SMase has been suggested as a major route for the production of ceramide in response to cellular stresses.

Abbr

SMase, Native (Bacillus cereus)

Alias

SMase

Source

Bacillus cereus

Applications

Sphingomyelinase has been used in a study to assess the interaction of actin with the HIV-1 accessory protein Nef. Sphingomyelinase has also been used in a study to investigate X-ray scattering as a quality-control tool for liposomal drug-delivery systems.

Form

Type I, buffered aqueous glycerol solution, Solution in 50% glycerol containing 50 mM Tris-HCl, pH 7.5; Type II, Lyophilized powder containing potassium phosphate buffer salts and stabilizer.

Enzyme Commission Number

EC 3.1.4.12

Activity

> 100 units/mg protein

CAS_No

9031-54-3

Unit Definition

One unit will hydrolyze 1.0 μmole of TNPAL-sphingomyelin per min at pH 7.4 at 37°C.

Storage

2-8°C

Synonyms

Sphingomyelin phosphodiesterase; EC 3.1.4.12; neutral sphingomyelinase; 9031-54-3; sphingomyelin cholinephosphohydrolase; sphingomyelinase; SMase

"SMase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0673	Native Staphylococcus aureus Sphingomyelinase	EC 3.1.4.12	9031-54-3	Staphylococcus aureus	Inquiry
NATE-1160	Native Sphingomyelinase from Streptomyces sp.	EC 3.1.4.12	9031-54-3	Streptomyces sp.	Inquiry
EXWM-3712	sphingomyelin phosphodiesterase	EC 3.1.4.12	9031-54-3		Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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