Native Bacillus sp. Uricase

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Cat No.

DIA-276

Description

The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2

Abbr

Uricase (Bacillus sp.)

Alias

UO; uricase

Source

Bacillus sp.

Applications

This enzyme is useful for enzymatic determination of uric acid in clinical analysis.

Appearance

White amorphous powder, lyophilized

Activity

GradeⅡ 1.5U/mg-solid or more

Contaminants

Catalase <1.0%

Molecular Weight

approx.150,000

Isoelectric point

4.7

pH Stability

pH 6.0-9.5 (25°C, 20hr)

Michaelis Constant

1.36×10⁻⁵M (Uric acid)

Structure

4 subunits per molecule

Unit Definition

One unit causes the oxidation of one micromole of uric acid per minute under the conditions described below.

Optimum pH

8.5

Optimum temperature

45°C

Thermal stability

below 60°C (pH 8.0, 10min)

Stability

Stable at -20°C for at least 6 months

Stabilizers

Borate, EDTA, nonionic detergents

Inhibitors

Ag⁺,Hg⁺⁺

Synonyms

urate oxidase; uric acid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II

"UO" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
DIA-173	Native Bacillus fastidiosus Uricase	EC 1.7.3.3	9002-12-4	Bacillus fastidiosus	Inquiry
DIA-175	Native Candida sp. Uricase	EC 1.7.3.3	9002-12-4	Candida sp.	Inquiry
DIA-294	Uricase, Recombinant	EC 1.7.3.3	9002-12-4		Inquiry
DIA-404	Uricase from Candida utilis, Recombinant	EC 1.7.3.3	9002-12-4	Escherichia coli	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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