Native Bovine Deoxyribonuclease I RNase-free solution

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Cat No.

NATE-0199

Description

Deoxyribonuclease I (usually called DNase I), is an endonuclease coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. It acts on single-stranded DNA, double-stranded DNA, and chromatin. In addition to its role as a waste-management endonuclease, it has been suggested to be one of the deoxyribonucleases responsible for DNA fragmentation during apoptosis.

Abbr

DNASE1, Native (Bovine)

Alias

DNASE1; DNase I

Source

Bovine pancreas

Species

Bovine

Applications

Used in molecular biology applications for removing DNA during RNA purification, for preparing DNA for nick translation, and for DNA-protein interaction analysis by footprinting methods.

Form

buffered aqueous glycerol solution.

Enzyme Commission Number

EC 3.1.21.1

CAS_No

9003-98-9

Molecular Weight

mol wt 29.1 kDa

Unit Definition

One unit will cause a ΔA260 of 0.001 per min per mL reaction mixture using calf thymus DNA as substrate.

Storage

−20°C

Function

actin binding; deoxyribonuclease I activity; endodeoxyribonuclease activity

Synonyms

DNASE1; deoxyribonuclease I; deoxyribonuclease-1; DNase I; 9003-98-9; EC 3.1.21.1; pancreatic DNase; DNase; thymonuclease, dornase; dornava; dornavac; pancreatic deoxyribonuclease; pancreatic dornase; deoxyribonuclease (pancreatic); pancreatic DNase; DNAase; deoxyribonucleic phosphatase; alkaline deoxyribonuclease; alkaline DNase; endodeoxyribonuclease I; DNA depolymerase; Escherichia coli endonuclease I; deoxyribonuclease A; DNA endonuclease; DNA nuclease

"DNASE1" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1875	Native Bovine Deoxyribonuclease I	EC 3.1.21.1	9003-98-9	Bovine Spleen	Inquiry
NATE-0198	Native Bovine Deoxyribonuclease I	EC 3.1.21.1	9003-98-9	Bovine pancreas	Inquiry
NATE-0200	Deoxyribonuclease I from Bovine, Recombinant	EC 3.1.21.1	9003-98-9	Pichia pastoris	Inquiry
NATE-1153	Deoxyribonuclease B, Recombinant	EC 3.1.21.1		Escherichia coli	Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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