Native Human Cathepsin S

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Cat No.

NATE-0178

Description

Cathepsin S is a lysosomal cysteine protease found primarily in the spleen and in lung macrophages. Its level is elevated in the brain tissue of those with Alzheimer's disease and Down syndrome. Cathepsin S may function in the processing of amyloid precursor protein to amyloid beta peptides.

Abbr

CTSS, Native (Human)

Alias

CTSS

Source

Human spleen

Species

Human

Applications

Cathepsin S from human spleen has been used in a study to assess the sequence identification, tissue distribution and polymorphism of the porcine cathepsin D (CTSD) Gene. Cathepsin S from human spleen has also been used in a study to investigate a new promising camptothecin analogue-polysaccharide conjugate.

Form

lyophilized powder. Lyophilized from 100 mM sodium acetate, pH 5.5, and 1 mM EDTA.

Enzyme Commission Number

EC 3.4.22.27

Unit Definition

One unit will hydrolyze Z-Val-Val-Arg-NHMec to yield 2 nanomoles of 7-amino-4-mehtylcoumarin in 10 minutes at pH 6.5 at 25°C

Storage

−70°C

Pathway

Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing and presentation, organism-specific biosystem; Endosomal/Vacuolar pathway, organism-specific biosystem

Function

cysteine-type endopeptidase activity; peptidase activity

Synonyms

CTSS; cathepsin S; EC 3.4.22.27; FLJ50259; MGC3886

"CTSS" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1702	Cathepsin S from Human, recombinant	EC 3.4.22.27	71965-46-3	E. coli	Inquiry
EXWM-4201	cathepsin S	EC 3.4.22.27	71965-46-3		Inquiry

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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