Native Microbial Xanthine Oxidase

inquiry

Cat No.

NATE-0733

Description

Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species. Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c.

Abbr

XO, Native (Microbial)

Alias

XO; XOD

Source

Microbial

Applications

This enzyme is useful for enzymatic determination of inorganic phosphorus, 5′-nucleotidase and adenosine deaminase when coupled with Purine-nucleoside phosphorylase and uricase.

Product Overview

Allopurinol is a synthetic drug show to inhibit xanthine oxidase.

Form

Lyophilized powder containing BSA and sodium glutamate as stabilizers

Enzyme Commission Number

EC 1.17.3.2.

Activity

> 7 units/mg solid

CAS_No

9002-17-9

Molecular Weight

mol wt ~160 kDa

pH Stability

pH 6.5-9.0 (25°C, 15hr)

Unit Definition

One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25°C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.

Optimum pH

7.5-8.0

Optimum temperature

65°C

Thermal stability

below 55°C (pH 8.0, 30min)

Storage

−20°C

Inhibitors

Reducing agents, Hg++, Ag+,MIA

Synonyms

Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase

"XAO" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
DIA-218	Native Microorganism Xanthine oxidase	EC 1.1.3.22	9054-84-6	Microorganism	Inquiry
NATE-0732	Native Bovine Xanthine Oxidase	EC 1.17.3.2.	9002-17-9	Bovine milk	Inquiry

Name:

Email *

Phone:*

Company/Institution:

Country or Region:

Quantity:

Services & Products Interested *

Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

Products

Online Inquiry