Native Pseudomonas sp. Polymyxin Acylase

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Cat No.

NATE-0611

Description

Polymyxin acylase, from Pseudomonas sp. deacylates polymyxin group antibiotics and long-chain fatty acyl groups of proteins. Polymyxin acylase has an affinity for long-chain fatty acyl proteins in human carcinoma cells.

Abbr

Polymyxin Acylase, Native (Pseudomonas sp.)

Source

Pseudomonas sp.

Applications

Polymyxin acylase, from Pseudomonas sp., is a N-myristoyl cleaving enzyme that has been used to determine the N-myristoyl peptide sequence and may be useful in cancer research since it has antitumor activity against murine and human tumor cells.

Activity

> 0.1 units/mg solid

CAS_No

111174-43-7

Unit Definition

One unit will hydrolyze 1 μmole of N-octanoyl-5-aminovaleric acid per min at pH 8.0 at 37°C.

Stability

−20°C

Synonyms

Polymyxin Acylase; Peptide N-fatty acylase

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Our Products Cannot Be Used As Medicines Directly For Personal Use.

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