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Enzymes for Research, Diagnostic and Industrial Use

Native Rabbit L-Lactic Dehydrogenase

Cat No.
NATE-0413
Description
Native Rabbit L-Lactate Dehydrogenase for research on lactate metabolism and enzymatic activity. Ideal for biochemistry and molecular biology studies. Creative Enzymes delivers trusted products.
Abbr
L-LDH, Native (Rabbit)
Alias
L-LDH; LAD; LD
Source
Rabbit muscle
Species
Rabbit
Product Overview
Lactic Dehydrogenase (LDH) has a total molecular weight of 140 kDa and is composed of 4 subunits which are designated M subunit (muscle) and H subunit (heart). These subunits may be mixed in any of 5 combinations (M4, M3H1, M2H2, MH3, and H4). Skeletal muscle contains LDH that is predominately M4 with some small amounts of M3H and traces of H2H2. The H and M subunits are quite similar in molecular weight, but differ substantially in amino acid composition. Rabbit muscle LDH diss ociates into dimeric species (MW = ~70 kDa) in acetate-chloride at pH 5.0, the diss ociation is reversible. Bi ochemistry, 13, 3527-3531 (1974). Oxidizes glyoxylate and lactate.
Form
Type I, lyophilized powder; Type II, ; Type III, ammonium sulfate suspension, Crystalline suspension in 3.2 M (NH4)2SO4 solution, pH 6.0.
Enzyme Commission Number
EC 1.1.1.27
Activity
>90%. (>200U/mL)
CAS_No
9001-60-9
Isoelectric point
8.4-8.6
Unit Definition
One unit will reduce 1.0 μmole of pyruvate to L-lactate per min at pH 7.5 at 37°C.
Optimum pH
7.5
Storage
2-8°C
Warnings
Protein determined by biuret.
Synonyms
EC 1.1.1.27; 9001-60-9; lactic acid dehydrogenase; L (+)-nLDH; L-(+)-lactate dehydrogenase; L-lactic dehydrogenase; L-lactic acid dehydrogenase; lactate dehydrogenase; lactate dehydrogenase NAD-dependent; lactic dehydrogenase; NAD-lactate dehydrogenase; L-lactate dehydrogenase; (S)-Lactate:NAD+ oxidoreductase; L-LDH; LAD; LD; Lactate

"LDH" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-1793 L-Lactate Dehydrogenase (Crude Enzyme) EC 1.1.1.27 9001-60-9 E. coli Inquiry
NATE-1681 Native Human Lactate Dehydrogenase EC 1.1.1.27 9001-60-9 Human Muscle Inquiry
NATE-1680 Native Human Lactate Dehydrogenase EC 1.1.1.27 9001-60-9 Human Heart Inquiry
NATE-1105 L-Lactate Dehydrogenase from Porcine, Recombinant EC 1.1.1.27 9001-60-9 Porcine Inquiry

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