Necrosis Inhibitor, Necrox-2

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Cat No.

CEI-0583

Description

A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1 µM NecroX-2 prevented ~50% cell death in H9C2 cells exposed to 400 µM t-BuOOH for 2 hours). Does not protect against staurosporine or etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro.

Appearance

Liquid

Product Overview

A necrosis inhibitor

Molecular Weight

654.7

Purity

>99% by HPLC

Storage

-20 centigrade

Targets

Necroptosis

Molecular Formula

C 25 H 32 N 4 O 4 S 2

Chemical Name

[5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(1-methanesulfonyl-piperidin-4-yl)-amine

Shipping Conditions

Gel pack

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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